6-morpholino-3-pyridinyl isothiocyanate
6-morpholino-3-pyridinyl isothiocyanate
CAS: 52024-29-0
Molecular Formula: C10H11N3OS
6-morpholino-3-pyridinyl isothiocyanate - Names and Identifiers
6-morpholino-3-pyridinyl isothiocyanate - Physico-chemical Properties
| Molecular Formula | C10H11N3OS |
| Molar Mass | 221.28 |
| Density | 1.28±0.1 g/cm3(Predicted) |
| Boling Point | 422.6±45.0 °C(Predicted) |
| Flash Point | 209.4°C |
| Vapor Presure | 0mmHg at 25°C |
| pKa | 2.83±0.10(Predicted) |
| Refractive Index | 1.645 |
6-morpholino-3-pyridinyl isothiocyanate - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
6-morpholino-3-pyridinyl isothiocyanate - Introduction
6-morpholino-3-pyridinyl isothiocyanate(6-morpholino-3-pyridinyl isothiocyanate) is an organic compound with the chemical formula C9H9N3OS.
Nature:
6-morpholino-3-pyridinyl isothiocyanate is a yellow solid with a pungent odor. It is soluble in organic solvents such as dimethyl sulfoxide (DMSO), benzene and chloroform, but insoluble in water.
Use:
6-morpholino-3-pyridinyl isothiocyanate is a commonly used functional reagent, often used in organic synthesis and biochemical research. It can be used for stereoselective synthesis, such as synthesis of functional compounds and derivatives containing isothiocyanate groups. In addition, it is also commonly used in the synthesis of biologically active molecules, such as antibacterial agents, anti-cancer drugs, etc.
Preparation Method:
6-morpholino-3-pyridinyl isothiocyanate can be obtained by reacting the isomeric isopropyl-N-(morpholino) chlorocarboxamide of the product with sodium sulphonate. The specific synthesis method can also use other reaction routes, but the common preparation method is to synthesize by nucleophilic substitution reaction in organic synthetic chemistry.
Safety Information:
6-morpholino-3-pyridinyl isothiocyanate is irritating to the eyes, skin and mucous membranes and should be avoided. Appropriate personal protective measures should be taken during work, such as wearing protective glasses, gloves and protective clothing. When using, avoid inhaling its powder or mist, and ensure that the operation is carried out in a well-ventilated environment. In case of accidental application or contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
Nature:
6-morpholino-3-pyridinyl isothiocyanate is a yellow solid with a pungent odor. It is soluble in organic solvents such as dimethyl sulfoxide (DMSO), benzene and chloroform, but insoluble in water.
Use:
6-morpholino-3-pyridinyl isothiocyanate is a commonly used functional reagent, often used in organic synthesis and biochemical research. It can be used for stereoselective synthesis, such as synthesis of functional compounds and derivatives containing isothiocyanate groups. In addition, it is also commonly used in the synthesis of biologically active molecules, such as antibacterial agents, anti-cancer drugs, etc.
Preparation Method:
6-morpholino-3-pyridinyl isothiocyanate can be obtained by reacting the isomeric isopropyl-N-(morpholino) chlorocarboxamide of the product with sodium sulphonate. The specific synthesis method can also use other reaction routes, but the common preparation method is to synthesize by nucleophilic substitution reaction in organic synthetic chemistry.
Safety Information:
6-morpholino-3-pyridinyl isothiocyanate is irritating to the eyes, skin and mucous membranes and should be avoided. Appropriate personal protective measures should be taken during work, such as wearing protective glasses, gloves and protective clothing. When using, avoid inhaling its powder or mist, and ensure that the operation is carried out in a well-ventilated environment. In case of accidental application or contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 15:17:58
